A vast array of software is required to run an efficient and successful healthcare organization, and all software developed for this purpose must be fully HIPAA-compliant and hosted on HIPAA-compliant infrastructure. The Health Insurance Portability and Accountability Act (HIPAA) sets the standard for sensitive patient data protection. Companies that deal with protected health information (PHI) must have physical, network, and process security measures in place and follow them to ensure HIPAA Compliance. Ā 

HIPAA regulation applies to all healthcare websites or software applications, and developers have to meet the mandatory requirements of HIPAA, paying particular attention to how PHI is accessed, and what data must be fully encrypted. This includes implementing stringent access controls, audit trails, and data encryption for information both in transit and at rest. Following these rules ensures that all protected health information (PHI) is safely stored, transmitted, and accessed by an application, safeguarding patient privacy and protecting the organization from significant penalties.

Why Do You Need Help from a HIPAA-compliant Software Developer?

Because developers must adhere to strict regulations, the development of HIPAA-compliant software is a complex and time-consuming process. Choosing a leading software company to develop HIPAA-compliant solutions is essential to meet the growing technical needs of your healthcare organization. You should research your options carefully and be sure to work with a software development company that has extensive experience in constructing HIPAA-compliant software solutions.

To help you choose a trusted and experienced partner, we have collated a list of the top 14 HIPAA-compliant software developers. These are development houses that meet and exceed the physical, technical and administrative safeguards of HIPAA. In compiling our list, we have considered each company’s experience in providing solutions to healthcare providers, reviews from previous clients, and their market presence.

1. Arkenea

Award-Winning Software Development Firm | Arkenea Inc
Arkenea, ranked among the top preferred healthcare software development companies, provides healthcare organizations with robust and scalable HIPAA-compliant mobile and web applications. Arkenea is the only software development company that is fully dedicated to the healthcare industry. The company has over 9 years of experience providing clients with software solutions that adhere to HIPAA and HITRUST regulations.

  • Exclusive Healthcare Focus: Arkenea dedicates its entire practice to the healthcare sector, ensuring deep domain expertise in building solutions like patient portals, EHR/EMR systems, and practice management software.
  • Regulatory Compliance Expertise: The team possesses profound knowledge of HIPAA and HITRUST regulations, building security and privacy protocols directly into the software development lifecycle from the initial design phase.
  • Custom Web & Mobile Applications: They specialize in creating bespoke, user-friendly applications for both web and mobile platforms, designed to improve clinical workflows and enhance patient engagement securely.

2. Mobisoft Infotech

Custom Software Development Company | AI-Driven Solutions

Mobisoft Infotech is a leading software development company specializing in delivering HIPAA-compliant healthcare solutions to organizations worldwide. With over 13 years of experience in developing innovative mobile and web applications, Mobisoft Infotech offers end-to-end services from custom software development to integration, testing, and maintenance. The company is committed to creating secure, scalable, and compliant solutions that meet the highest standards of the healthcare industry, ensuring full adherence to HIPAA and HITRUST regulations. Trusted by top-tier healthcare providers, Mobisoft Infotech empowers organizations with digital solutions that enhance patient care, streamline operations, and drive healthcare innovation.

  • End-to-End Development Services: Mobisoft Infotech manages the entire product lifecycle, from initial consultation and strategic planning through to development, deployment, and ongoing maintenance and support.
  • Innovative Digital Health Solutions: The company leverages its extensive experience to build cutting-edge applications for telemedicine, remote patient monitoring, and digital therapeutics that are fully secure and scalable.
  • Global Delivery Model: With a worldwide presence, they offer flexible engagement models and a robust delivery framework to serve a diverse range of healthcare clients, from startups to large enterprises.

3. Technology Rivers

Technology Rivers | Healthcare, AI & Mobile Software Development Agency
Technology Rivers is a Virginia based custom software development firm, that specializes in HIPAA compliant web and mobile app development. Technology Rivers work with healthcare entrepreneurs, startups, and health-tech organizations and help them in creating innovative healthcare solutions. Their work includes native and cross-platform hybrid mobile apps, web applications, desktop applications, and integrations with EMR & EHR such as EPIC.

  • EMR & EHR Integration Specialists: The company excels at creating seamless integrations with major electronic health record systems like EPIC, ensuring that new applications work flawlessly within existing clinical IT ecosystems.
  • Startup and Innovator Focused: Technology Rivers partners with health-tech entrepreneurs and startups, providing the technical expertise needed to turn innovative ideas into market-ready, compliant software products.
  • Cross-Platform Development: They possess strong capabilities in developing both native and hybrid mobile applications, offering clients the flexibility to reach users on any device without compromising on performance or security.

4. Novelty Technologies

Chronicles | Novelty Technology

Our friends at Novelty Technologies provide end-to-end software solutions for many clients, including high-profile healthcare organizations. Novelty Technologies caters to the entire development lifecycle, from web/mobile app creation and UI/UX design to data analytics and API integration. Novelty has vast experience working with HIPAA compliant hosting partners, and security underpins their entire design process.

  • Full-Lifecycle Project Management: Novelty Technologies oversees every stage of development, from initial concept and UI/UX design to backend engineering, API integration, and powerful data analytics implementation.
  • Security-First Design Philosophy: Security is not an afterthought but a core component of their design process, ensuring every application is built from the ground up to protect PHI and meet regulatory standards.
  • Expertise in Compliant Hosting: The team has extensive experience collaborating with HIPAA-compliant hosting providers, allowing them to architect and deploy applications within a secure and resilient infrastructure.

5. ZDI

It's official. ZDI has joined forces with Stirista, one of the world's leading data-driven marketing technology companies!, Link in bio!, @stirista , #brandingfirm #marketingdigital #marketingcreative ...
ZDI is a leading digital marketing company and a proud partner of Atlantic.Net. ZDI has strong ties with HIPAA compliant organizations and provides a number of services to healthcare clients, including website and mobile app design, brand creation, and content creation. ZDI won the GDUSA Health + Wellness Design award in 2017 and has created some excellent web applications for our clients.

  • Healthcare Marketing and Design: ZDI combines technical development with a strong focus on digital marketing, helping healthcare organizations create a powerful brand presence through compelling web design and content strategy.
  • Award-Winning Design Acumen: As a winner of the GDUSA Health + Wellness Design award, ZDI demonstrates a proven ability to create visually appealing and highly functional web and mobile applications for the health sector.
  • Comprehensive Service Offering: Their services extend beyond simple development to include brand creation, patient-facing content development, and strategic marketing, providing a holistic solution for healthcare clients.

6. Let’s Talk Interactive

End-to-End Telehealth Solutions | AI-Powered RPM & Global Virtual…
Let’s Talk Interactive has been doing amazing things for our friends in healthcare before, during, and after the Covid-19 pandemic. Telemedicine has become the first choice for frontline healthcare workers, and Let’s Talk provides HIPAA-compliant teleconferencing services as well as industry-leading virtual and walk-in clinic software, empowering healthcare professionals to conduct vital assessments of patients remotely over the phone or via video chat.

  • Telemedicine and Virtual Care Platforms: They are a leader in providing comprehensive, HIPAA-compliant telehealth solutions, including secure video conferencing and software for managing virtual clinics and patient appointments.
  • Remote Patient Assessment Tools: Their software empowers clinicians to conduct vital remote assessments, bridging the distance between provider and patient and expanding access to care, especially in critical situations.
  • Proven Pandemic Response: The company has a demonstrated track record of supporting healthcare providers with reliable and scalable virtual care technology, proving its value during peak demand periods.

7. MobiDev

MobiDev Releases Mobile Device Management Guide 2022
MobiDev is a custom software development company awarded as Best Upwork Software Development Agency 2016-2019. Having comprehensive experience of more than 10 years, MobiDev provides HIPAA-compliant mobile and web solutions integrated with the latest innovative technologies: Artificial Intelligence, Machine Learning, The Internet of Things, and Augmented Reality.

  • Advanced Technology Integration: MobiDev specializes in embedding next-generation technologies like AI for diagnostics, IoT for remote monitoring, and AR for surgical training into its HIPAA-compliant software solutions.
  • Recognized Development Excellence: With multiple awards for their quality and client satisfaction, MobiDev has established itself as a trusted partner for complex custom software projects in the healthcare domain.
  • Cross-Domain Expertise: Their decade of experience spans multiple industries, allowing them to bring fresh perspectives and innovative approaches to solving unique challenges within healthcare technology.

8. VAIRIX Software Development

VAIRIX | Nearshore Software Development & Staff Augmentation
VAIRIX Software Development is a nearshore software development company with extensive experience building HIPAA-compliant health and wellness apps. From virtual consultation and e-prescriptions to mental health counseling and support group functionalities, their team of experts craft products that help your users seamlessly manage their medical needs. Based out of Montevideo, Uruguay (UTC-3), VAIRIX provides staff augmentation and end-to-end development services to clients across the United States.

  • Nearshore Development Model: Based in a US-friendly time zone, VAIRIX offers real-time collaboration and cost-effective development services, making them an ideal partner for American healthcare companies.
  • Health and Wellness App Specialization: The team has deep expertise in creating consumer-facing applications for managing medical needs, including virtual consultations, e-prescribing, and mental health support platforms.
  • Flexible Engagement Options: VAIRIX provides both full end-to-end project development and staff augmentation, allowing clients to either outsource an entire project or supplement their in-house team with skilled developers.

9. Inoxoft


Inoxoft is a certified custom healthcare software development company. It offers custom healthcare solutions done by high-skilled professionals with considerable domain expertise. They’ve delivered top-notch medical software for a range of medical service institutions. Their clients are hospitals as well as healthcare startups whom They offer custom medical software development services. They’ll empower you with new ideas on how to leverage medical care. Building custom healthcare solutions Inoxoft engineers work with up-to-date technologies such as Python, .Net, Node.js, ReactJS, Flutter, and React Native.

  • Certified Domain Expertise: As a certified healthcare development company, Inoxoft brings a high level of professionalism and domain-specific knowledge to projects for both established hospitals and innovative startups.
  • Modern Technology Stack: Their engineers are proficient in a wide range of modern technologies, including Python, .Net, and React, enabling them to build high-performance, scalable, and secure healthcare applications.
  • Client-Centric Innovation: Inoxoft prides itself on empowering clients with new ideas and strategies for leveraging technology to improve patient care, streamline operations, and drive better clinical outcomes.

10. Archer Software

Archer Software Software Development

Archer Software is an innovative technology consulting and custom software development company that helps startups and enterprises digitize the healthcare domain. Established in 2000, Archer Software builds HIPAA compliant healthcare solutions and wellness apps, having designed, built, and supported more than 650 B2B, B2C, and B2G products for 400+ clients. They help their global high-tech clients deliver life-changing solutions providing technology consulting, product design, and digital solutions development as well as agile transformation.

  • Extensive Project Portfolio: With over two decades of experience and more than 650 products delivered, Archer Software has a vast and proven track record of successfully building and supporting complex healthcare solutions.
  • Strategic Technology Consulting: Beyond coding, they offer high-level technology consulting and product design services to help clients navigate the complexities of digital transformation and healthcare compliance.
  • Diverse Client Experience: They have a long history of working with a wide range of clients, from startups to large enterprises and government entities (B2B, B2C, and B2G), adapting their approach to fit diverse needs.

11. Belitsoft

Belitsoft Company Profile | Reviews | Portfolio - TopDevelopers.co
Belitsoft has been delivering technology solutions and services for the healthcare industry since 2015. The company focuses on long-term partnerships with its clients from the United States, the UK, Europe, and Israel. Belitsoft’s clients include healthcare startups, medical ISVS, hospitals, healthcare centers, private medical practices, pharmacy organizations, medical and research laboratories.Ā Belitsoft engages with third-party security auditors, such as OWASP and TrueSec, to guarantee safety and compliance with health IT standards and regulations.

  • Third-Party Security Validation: Belitsoft reinforces its commitment to security by engaging with reputable third-party auditors like OWASP and TrueSec, providing clients with an extra layer of assurance.
  • Long-Term Partnership Focus: The company culture is built around forming durable, long-term relationships with clients, ensuring continuous support and evolution of the software solutions they provide.
  • Broad Healthcare Clientele: They serve a diverse spectrum of the healthcare ecosystem, including hospitals, private practices, research labs, and pharmacies, giving them a holistic understanding of the industry’s needs.

12. TatvaSoft

Tatvasoft | Drupal.org
TatvaSoft specializes in healthcare software development with over 18 plus years of experience in developing custom software applications. They create HIPAA-compliant web, desktop, and mobile app solutions. They offer a broad spectrum of healthcare solutions such as EHR systems, telemedicine, medical health applications for both patients and healthcare management professionals.

  • Multi-Platform Development: TatvaSoft has deep expertise in creating integrated solutions across web, desktop, and mobile platforms, ensuring a consistent and seamless user experience for patients and providers alike.
  • Wide Range of Healthcare Solutions: Their portfolio includes everything from complex Electronic Health Record (EHR) systems to user-friendly telemedicine platforms and practice management tools, showcasing their versatile capabilities.
  • Decades of Experience: With over 18 years in the custom software industry, TatvaSoft brings a wealth of experience and a mature development process to every healthcare project they undertake.

13. ScienceSoft

Contact Us - ScienceSoft
ScienceSoftĀ is an ISO 13485:2016, ISO 9001:2015, ISO 27001:2013 certified IT consulting and software development company with 16 years of healthcare IT experience, headquartered in McKinney, Texas, US, with offices in Europe and the Middle East. Experienced in HIPAA-compliant software development, ScienceSoft delivers software to leading healthcare organizations.

  • Multiple ISO Certifications: ScienceSoft’s adherence to major ISO standards for quality management, medical devices, and information security demonstrates a formal commitment to the highest levels of quality and security.
  • Deep Healthcare IT Consulting: With 16 years of dedicated experience, the company provides expert IT consulting in addition to software development, helping organizations optimize their technology strategies and compliance posture.
  • Global Presence, Local Expertise: Headquartered in Texas with international offices, ScienceSoft combines a global talent pool with localized expertise to serve leading healthcare organizations around the world.

14. IT Craft

IT Craft: Software Development Company
IT Craft is a leader within the software development industry, having recently been recognized as the ā€œTop Web Developers, 2020ā€ by Clutch, an independent research company based in Washington D.C. What sets IT Craft apart is its commitment to support clients through the completion of their project and beyond, providing all of its partners with high-quality post-launch support. This custom medical software provider delivers the development of new healthcare-related mobile and web applications, as well as the improvement and performance optimization of existing applications.

  • Post-Launch Support Commitment: IT Craft distinguishes itself with a strong focus on long-term partnerships, providing comprehensive post-launch support and maintenance to ensure applications remain secure and effective over time.
  • Award-Winning Development Team: Recognition as a top developer by industry research firms like Clutch validates their technical skill and ability to deliver high-quality web and mobile applications for their clients.
  • New and Legacy System Expertise: They are skilled in both building brand-new healthcare applications from scratch and in modernizing, improving, and optimizing existing legacy software systems for better performance.

How Can Atlantic.Net Help?

The rapidly evolving field of healthcare technology can be a minefield for many healthcare professionals looking for compliant software solutions. With an ever-increasing workload, medical professionals are embracing new cloud-based platforms to improve the quality and speed of patient care. While technological advances can make life much easier for, already stretched, medical staff, ensuring the safety and security of confidential patient information can bring a new headache.

As a healthcare provider, no matter what software solution you purchase, you must choose a fully HIPAA-compliant hosting platform that will prioritize security, privacy, and compliance to host the application. Atlantic.Net can offer you cloud hosting solutions that are fully scalable and customizable to meet the needs of your organization. Contact our sales team today to find out how Atlantic.Net can help your organization.

This article was updated on October 14, 2025.